GlutaminOx

Description:

GlutaminOx provides free L-glutamine as a pleasant tasting, moderately soluble powder in 5g sachets.

Typical Nutritional Information:

Providing:                                      Per 5g Sachet

Energy (Kcal)                                         20

            (Kj)                                            84

Utilisable Nitrogen (g)                            0.96

L-glutamine (g)                                        5

Actions:

GlutaminOx products provide free L-glutamine; a nutritional supplement, which may be indispensable in times of critical illness. Plasma glutamine levels are raised within 30 minutes of GlutaminOx oral ingestion and are maintained for at least two hours. (1,2)

Indications:

GlutaminOx can be recommended to provide free L-glutamine in times of critical illness or metabolic stress. Glutamine is known to:

Maintain gut integrity and possibly prevent bacterial translocation. (3)

Provide a source of energy for the immune system and the gut. (3,4)

Provide amino nitrogen for alanine production. (5)

Promote lymphocyte and macrophage proliferation. (6)

Reduce mortality and intensive care costs. (7)

Improve resistance to infection (8)

GlutaminOx products enable adult and paediatric patients to receive glutamine supplementation during and after leaving the Intensive Care Unit.

Dosage:

Dosage should be determined by the physician or dietitian only. Recommended dosage 0.3g/kg/day. (1)

(ADULTS: 3-4 sachets of GlutaminOx 5 per day)

(CHILDREN: 1-2 sachets of GlutaminOx 5 per day)

Preparation:

GlutaminOx sachets are versatile and easily prepared. They may be dissolved in water, soft drinks, milky tea or coffee (9), sprinkled onto food, flushed through the tube during enteral feeding or added to a standard enteral feeding solution. After preparation, GlutaminOx should be refrigerated, if not used immediately, but must not be kept for longer than 24 hours.

Packaging:

GlutaminOx products are available in boxes of 50, 100 or 400

GlutaminOx sachets have a three year expiry date

References:

(1) T.R. Ziegler, R.J. Smith, T.A. Byrne, D.W. Wilmore. Potential role of glutamine supplementation in nutrition support. Clinical Nutrition; 12 (suppl.1): S82-S90, 1993.

(2) L.M. Castell, G. Hardy, S.J. Bevan, E.A. Newsholme. Enteral glutamine administration in humans. Poster presentation. BAPEN 1993.

(3) D.W. Wilmore, R.J. Smith, S.T. O’Dwyer, et al. The gut: A central organ after surgical stress. Surgery; 104: 917-923, 1988.

(4) E.A. Newsholme. Importance of glutamine in nutrition of the immune system. Clinical Nutrition; 14: 129, 1995.

(5) R.J. Smith. Glutamine metabolism and its physiological importance. Journal of Parenteral and Enteral Nutrition; 14: 405-445, 1990.

(6) M. Parry-Billings, J. Evans, P.C. Calder, E.A. Newsholme. Does glutamine contribute to immunosuppression after major burns? Lancet; 336: 523-525, 1990.

(7) Griffiths RD, Jones C, Palmer TEA. Six month outcome of critically ill patients given glutamine-supplemented parenteral nutrition. Nutrition; 13(4): 295-302, 1997.

(8) Griffiths et al Nutrition 2002

(9) G. Hardy & H. Sladen. Stability of L-Glutamine in a variety of drinks for oral administration. Nutrition; 13: 7/8: 760, 1997.

For sales information or data sheets on our nutritional products please contact Oxford Nutrition customer services:  Tel: 01993 709752 Fax: 01993 709754 or email info@nutrinox.com